KMID : 0904020130290040138
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Journal of Korean Society for Vascular Surgery 2013 Volume.29 No. 4 p.138 ~ p.141
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Histopathological Changes of Venous Calcification in the Arterio-Venous Fistula for Hemodialysis
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Jung Hyuk-Jae
Lee Sang-Su
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Abstract
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Purpose: This study suggests that venous calcification (VC) may occur within the arterialized vein (AV) of patients with chronic renal failure. VC may be the cause of arteriovenous fistula (AVF) failure.
Methods: Specimens of AV were obtained during the removal of AVF to study morphological changes in the AV wall. We retrospectively analyzed 27 patients with AV specimens prepared and stained with hematoxylin and eosin, Masson¡¯s trichrome and Verhoeff van Gieson stains.
Results: Of the 27 patients, only 7 (4 males and 3 females, mean age 49.4 years) had evidence of VC in the AV (5 patients media only, 2 patients intima and media involved). AVF removal was done due to aneurym (3 cases), stenosis (2 cases), and kidney transplantation (2 cases). The mean duration from AVF construction to the repair of AVF was 88 months (range, 50 to 144 months). There were two cases of diabetes mellitus and hypertension in patients with VC.
Conclusion: VC may occur within the arterialized vein in chronic kidney disease patients after AVF construction.
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KEYWORD
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Venous calcification, Arterialized vein, Arteriovenous fistula
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